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March 19, 2026Medical RecordsOpen Access

Physical Function And Performance Effects Of Platelet-Rich Plasma (Prp) In Early-Stage Knee Osteoarthritis

Aziz Atik Bünyamin Arı Ali İhsan Kılıç

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Key Points

The study aims to evaluate the impact of platelet-rich plasma (PRP) on physical function and performance in patients with early-stage knee osteoarthritis.
Involved 80 patients with stage 1-2 bilateral knee osteoarthritis.
Applied intra-articular PRP injections at one-month intervals by the same physician.
Evaluated physical performance using Stair Climb Test, 50-Foot Walk Test, 30-second Chair Stand Test, and Timed Up and Go Test.
Recorded Hospital for Special Surgery knee scoring as a secondary outcome.
Used paired-t test for statistical analysis of pre- and post-injection results.
Significant improvement in all physical performance tests at 6 months after PRP application.
Statistically significant functional improvements measured through HSS scoring.
Improvements indicate enhanced mobility and reduced pain in patients post-treatment.

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Implication

Investigates PRP's effectiveness in improving physical function and performance in knee osteoarthritis, suggesting potential benefits for patients.

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Cite This Study

Atik et al. (2026) studied this question.

synapsesocial.com/papers/69be36766e48c4981c675715 https://doi.org/10.37990/medr.1752332

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Impact of platelet-rich plasma (PRP) intra-articular injection on functioning and kinematic analysis in knee osteoarthritis patients: A prospective observational studyObservational Study · 2026
2Platelet-Rich Plasma for Knee Osteoarthritis and Patient-Reported Outcomes: A Large Retrospective AnalysisCohort Study · 2026
3Clinical outcomes of intra-articular platelet-rich plasma injection in knee osteoarthritisCohort Study · 2026
4Clinical efficacy of single intra-articular platelet-rich plasma injections in mild to moderate knee osteoarthritis: a prospective study2025
5Effect of Intra-Articular Platelet-Rich Plasma (PRP) Injections on Gait Parameters and Patient-Reported Outcomes in Patients with Mild-to-Moderate Knee Osteoarthritis (Kellgren-Lawrence Grade I-II): A Prospective Single-Group Pre-Post Study2025

EFFICACY OF PLATELET-RICH PLASMA IN KNEE OSTEOARTHRITIS: A ONE-YEAR PROSPECTIVE FOLLOW-UP STUDY2019
Efficacy of intra-articular platelet -rich plasma in osteoarthritis knee2024
Effects of Platelet-Rich Plasma Injection in Knee Osteoarthritis Stages 1-4: A Retrospective Cohort Study2026
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