Anticancer, Anti-inflammatory, Analgesic, and Anxiolytic Effects of Koumine and Their Molecular Mechanisms

Koumine is an indole alkaloid monomer extracted from the Chinese herb Gelsemium elegans, which has a variety of pharmacological effects. This paper provides a comprehensive summary of the pharmacological effects and molecular mechanisms of koumine, with a particular emphasis on its mechanisms of action in the context of anticancer, anti-inflammatory, analgesic, and anxiolytic properties. The aim is to provide a theoretical foundation for further research and the application of koumine in clinical practice.