What question did this study set out to answer?

The central aim is to evaluate how medical therapies for endometriosis affect bone mineral density (BMD).

Effect of Medical Therapies for Endometriosis on Bone Health

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The central aim is to evaluate how medical therapies for endometriosis affect bone mineral density (BMD).
Systematic review of clinical studies from electronic databases until July 2025.
Included randomized controlled trials and cohort studies involving women of reproductive age.
Assessed various interventions such as GnRH agonists, dienogest, GnRH antagonists, and DMPA.
GnRH agonists led to a decrease in BMD at 6 months (−0.89%) and 12 months (−1.50%).
Dienogest was associated with decreased BMD at both 6 months (−0.83%) and 12 months (−1.91%).
GnRH antagonists showed a significant decrease in BMD at 6 months (−2.17%).

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Systematic review assesses hormonal treatments' impact on bone density in women with endometriosis, suggesting caution in management.

Désilets et al. (2026) studied this question.

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