The research aims to evaluate the diagnostic value of dual positivity for specific antibodies in primary biliary cholangitis (PBC).
Comparison of antibody positivity in diagnosing PBC against histopathology.
Assessment of dual positivity for AMA/AMA-M2 and anti-gp210/sp100.
Dual positivity for AMA/AMA-M2 and anti-gp210/sp100 demonstrated the highest diagnostic accuracy for PBC.
Findings emphasize the significance of specific antibody testing in clinical diagnostics.
Abstract
Histopathology remains the definitive standard for diagnosing PBC. Dual positivity for AMA/AMA-M2 and anti-gp210/sp100 showed the highest diagnostic value in identifying PBC.