Secondary analysis finds nicotine titration in smokers using alternative systems, suggesting wider access could enhance reduction interventions.
Most adults who smoke, when switched to very low nicotine content cigarettes, will use available alternative nicotine delivery systems (ANDS) to supplement their intake of nicotine. Provision of ANDS appears to be associated with a high degree of nicotine titration. Making less harmful ANDS widely available may make a mandated nicotine reduction intervention more acceptable to people who smoke. Clinical Trial Registration Details: NCT03272685.
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Benowitz et al. (2026) studied this question.
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