This analysis predicts corneal swelling due to oxygen flux through contact lenses, suggesting optimal oxygen tension levels.
After reviewing the oxygen needs of the cornea, we calculate the increase in corneal swelling which is predicted to occur for oxygen flux through a contact lens at the rate of less than 1.5 μl/cm 2 /hr. The amount of corneal swelling is inversely related to the oxygen flux into the anterior corneal surface. To keep corneal swelling below 4% requires an oxygen tension of about 11 mm Hg which is equivalent to a flux of 2 μl/cm 2 /hr.
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NATSUMEDA et al. (1981) studied this question.
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