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Study examines chromosomal deletions and monosomy in iris melanoma, suggesting biological behavior differences compared to choroidal melanoma.
The present study showed for the first time that deletions of the short arms of chromosomes 1 and 8 are detected 2.5 times more frequently, and monosomy of chromosome 3 occurs 1.5 times less frequently in iris melanoma compared to choroidal melanoma. The revealed features confirm the more favorable biological behavior of iris melanomas compared to choroidal melanomas.
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Saakyan et al. (2026) studied this question.
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