Retrospective analysis shows improved relapse-free survival in children with leukemia using cladribine, suggesting better outcomes.
Incorporation cladribine into conditioning regimens for pediatric ALL is associated with improved relapse-free survival and significantly lower frequencies of renal and gastrointestinal toxicities, without increasing the risk of transplant-related complications. Given the retrospective design and limited number of events, these promising findings warrant prospective validation in future studies.
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Li et al. (2026) studied this question.
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