Key result
Endothelial dysfunction drives early atherosclerosis and HF, offering a reversible therapeutic target.
Design
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Warrants endothelial assessment in at-risk patients for timely intervention; extends research into therapies reversing early cardiovascular injury.
Rakesh Kumar Sharma (2026) studied this question. Endothelial dysfunction serves as a reversible, early marker of cardiovascular injury that drives atherosclerosis and heart failure, offering a key target for early therapeutic intervention.
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