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March 21, 2026The International Journal of Artificial Organs2 citations

Cross-shaped nanoporous poly(methyl methacrylate) fibers for selective adsorption of β 2 -microglobulin and other middle-molecular-weight proteins

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HFHiroaki FujiedaTOTomoaki OsukaMNMasaru Nakada

Key Points

  • This research aims to develop cross-shaped PMMA fibers for the selective removal of β2-microglobulin and mid-weight proteins.
  • Optimization of cross-shaped PMMA fiber design
  • Assessment of adsorption efficiency for β2-microglobulin
  • Evaluation of flow dynamics for hemoperfusion applications
  • Enhanced selective adsorption of β2-microglobulin compared to other proteins
  • Improved flow characteristics suitable for hemoperfusion therapy applications

Abstract

Optimized cross-shaped PMMA fibers enable efficient, selective β2-MG removal and favorable flow dynamics for hemoperfusion therapies targeting mid-weight uremic toxins.

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Cite This Study

Fujieda et al. (2026) studied this question.

synapsesocial.com/papers/69be387d6e48c4981c678e97https://doi.org/10.1177/03913988261429904
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