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March 21, 2026PainOpen Access

Women with chronic pelvic pain can be stratified using multimodal assessment

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Authors

LDLysia DemetriouHammersmith HospitalLCLydia CoxonUniversity of OxfordEEEmma EvansUniversity of Oxford

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Implication

Reveals distinct subgroups of chronic pelvic pain in women, indicating new stratification strategies for better management.

Key Points

  • The research aims to phenotype chronic pelvic pain (CPP) in women using a multimodal assessment approach.
  • Integrated questionnaires, physiological, and biological data from 108 women with CPP and 50 pain-free controls.
  • Conducted group comparisons to evaluate differences in reported symptoms.
  • Utilized latent profile analysis to identify distinct subgroups of CPP.
  • CPP participants reported significantly greater fatigue, poorer sleep, increased anxiety, depression, and childhood trauma compared to controls.
  • No significant differences were found in physiological measures.
  • Three distinct subgroups of CPP were identified, primarily differentiated via questionnaire responses.

Cite This Study

Demetriou et al. (2025) studied this question.

synapsesocial.com/papers/69be387d6e48c4981c678fd2https://doi.org/10.1097/j.pain.0000000000003857
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