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March 21, 2026Atherosclerosis Plus0 citationsOpen Access

Association between HIV Infection and Arterial Stiffness: A Population-Based Cross-Sectional Study from Rakai, South Western Uganda.

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CBCharles BatteKarolinska InstitutetMNMartha NamusobyaMakerere UniversitySNShivan NuwasiimaMakerere University

Key Result

HIV infection significantly increased arterial stiffness among 370 participants in a Ugandan population-based sample, which had an overall arterial stiffness prevalence of 15.4%.

Key Points

  • This research aims to investigate the association between HIV infection and arterial stiffness in a population-based sample.
  • Conducted a cross-sectional study in Rakai, Uganda
  • Analyzed a population-based sample of 370 participants
  • Measured arterial stiffness and assessed HIV status
  • Prevalence of arterial stiffness was found to be 15.4% in the sample
  • HIV infection significantly increased arterial stiffness among participants

Structured PICO

Is HIV infection associated with increased arterial stiffness in a population-based sample in Sub-Saharan Africa?

P
Population
370 participants from a population-based sample in Rakai, South Western Uganda.
I
Intervention
HIV infection (exposure)
O
Outcome
Arterial stiffnesssurrogate

HIV infection is significantly associated with increased arterial stiffness in a Sub-Saharan African population, highlighting the need for cardiovascular risk assessment in this demographic.

Abstract

• Chronic HIV related inflammation and immune activation is independently associated with increased arterial stiffness. • Majority of people living with HIV are found in Sub-Saharan Africa however, few studies have assessed arterial stiffness in this population. • A prevalence (15.4%) of arterial stiffness was found in a population-based sample of 370 participants in Rakai, South Western Uganda. • HIV infection significantly increased arterial stiffness.

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Cite This Study

Batte et al. (2026) studied this question. HIV infection significantly increased arterial stiffness among 370 participants in a Ugandan population-based sample, which had an overall arterial stiffness prevalence of 15.4%.

synapsesocial.com/papers/69be38906e48c4981c6791c1https://doi.org/10.1016/j.athplu.2026.100559
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of HIV Infection and Antiretroviral Therapy With Arterial Stiffness: A Systematic Review and Meta-Analysis2021 · 21 citations
  2. 2Arterial Stiffness and Cardiovascular Events2010 · 2,225 citations
  3. 3Body Composition and Metabolic Changes in HIV-Infected Patients2012 · 133 citations
  4. 4Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV2018 · 989 citations
  5. 5Heterogeneity of the HIV epidemic in agrarian, trading, and fishing communities in Rakai, Uganda: an observational epidemiological study2016 · 211 citations