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A randomised controlled trial evaluates a physiotherapy intervention's effectiveness on motor skills and quality of life in children with ASD, suggesting potential benefits.
Children with Autism Spectrum Disorder (ASD) frequently experience psychomotor impairments, limited participation in physical activities, and reduced quality of life (QoL). Exercise shows promising benefits, but physiotherapy approaches in ASD are underreported, with limited evidence supporting a structured framework that systematically targets motor and functional outcomes. This study protocol describes a single-blinded randomised controlled trial evaluating the effectiveness of a structured physiotherapy intervention on motor skills, physical activity levels, and behavioural and QoL among children with mild to moderate ASD. This trial will include 64 children aged 6–10 years with ASD. Participants will be randomly assigned to an intervention group or a control group. Both groups will receive usual care therapy, equated between groups. The intervention group will also receive structured physiotherapy twice weekly for 12 weeks, each session lasting 60 minutes. The intervention integrates coordination, balance, strength, and endurance training. Outcome assessments will be conducted at baseline and post-intervention using validated instruments: GARS-3, BOT-2, GLTEQ, CBCL and PedsQL. Data analysis will follow the intention-to-treat principle and will examine between-group and within-group changes across all outcome measures. Qualitative data will be analysed using thematic analysis to characterise themes reflecting participants' engagement and parents' and caregivers' perspectives on the intervention.
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Alwi et al. (2026) studied this question.
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