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Observational study demonstrates efficacy and safety in clozapine monitoring, suggesting improved precision in treatment decisions.
These plasma clozapine levels aligned more with the DRR than with the TRR, particularly when individual dosing was considered. The DRR may offer higher precision in guiding therapeutic decisions and dose adjustments. Further prospective studies are warranted to optimize the use of the DRR in clinical practice and validate the value of the DRR in predicting clozapine efficacy and safety.
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Ferchichi et al. (2026) studied this question.
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