Engineering Anthraimidazoledione Charge-Transfer Fluorophores for Phospholipid Detection through Self-Assembly-Induced Emission

Sourav Mondal; Nilanjan Dey

doi:10.1039/d5sd00232j

January 1, 2025Sensors & DiagnosticsOpen Access

Engineering Anthraimidazoledione Charge-Transfer Fluorophores for Phospholipid Detection through Self-Assembly-Induced Emission

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Key Points

The research aims to design and synthesize fluorescent probes for the selective detection of cardiolipin at physiological pH.
Synthesis of anthraimidazoledione-based fluorescent probes
Evaluation of selectivity for cardiolipin in PBS buffer
Analysis of emission properties in response to phospholipid presence
The synthesized probes show selective fluorescence for cardiolipin at pH 7.0
Emission intensity significantly increases in the presence of cardiolipin
Demonstrated effectiveness in distinguishing cardiolipin from other phospholipids

Implication

Research reports engineering fluorescent probes to detect cardiolipin, suggesting a novel method for lipid analysis.

Abstract

Herein, we report the design and synthesis of anthraimidazoledione-based fluorescent probes for the selective detection of cardiolipin (CL) at pH 7.0 in PBS buffer. Compound 1, bearing a protonated tertiary...

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Cite This Study

Mondal et al. (2025) studied this question.

synapsesocial.com/papers/69be38ca6e48c4981c67961f https://doi.org/10.1039/d5sd00232j

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Engineering Anthraimidazoledione Charge-Transfer Fluorophores for Phospholipid Detection through Self-Assembly-Induced Emission

Key Points

Implication

Abstract

Discussion

Cite This Study

Engineering Anthraimidazoledione Charge-Transfer Fluorophores for Phospholipid Detection through Self-Assembly-Induced Emission

Key Points

Implication

Abstract

Discussion

Cite This Study

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