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March 21, 2026International Journal of PediatricsOpen Access

Real‐World Management of Pediatric Persistent and Chronic ITP: A Cross‐Sectional Study of Treatment Practices and Decision‐Making

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Authors

AAAli H. AlgiraigriKing Abdulaziz UniversityLALayan F. AlharbiKing Abdulaziz UniversityMAMaha AlharbiSaad Specialist Hospital

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Implication

Cross-sectional survey reveals treatment variability in pediatric ITP, suggesting a need for improved decision-making.

Key Points

  • This study aims to evaluate the management practices for pediatric persistent and chronic immune thrombocytopenia (ITP) in real-world settings.
  • Conducted a cross-sectional survey in January 2025 among pediatric hematologists.
  • Assessed diagnostic strategies including bone marrow aspiration (BMA) and immune workups.
  • Evaluated treatment preferences between rituximab and splenectomy.
  • 45.2% of respondents routinely used bone marrow aspiration despite guidelines favoring selective use.
  • Only 19.4% reported high confidence in interpreting immune workups.
  • Rituximab was preferred over splenectomy due to infection risk and its nonsurgical nature.

Cite This Study

Algiraigri et al. (2026) studied this question.

synapsesocial.com/papers/69be38ca6e48c4981c679640https://doi.org/10.1155/ijpe/3751986
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1American Society of Hematology 2019 guidelines for immune thrombocytopenia2019 · 1,422 citations
  2. 2Immune or inherited thrombocytopenia? A population‐based cohort study on children and adolescents presenting with a low platelet count2024 · 7 citations
  3. 3Long‐term follow‐up analysis after rituximab therapy in children with refractory symptomatic ITP: identification of factors predictive of a sustained response2008 · 61 citations
  4. 4Pediatric refractory immune thrombocytopenia: A systematic review2022 · 17 citations