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Decoding the actionable potential of ribosome biogenesis in acute myeloid leukemia | Synapse
March 21, 2026
Open Access
Decoding the actionable potential of ribosome biogenesis in acute myeloid leukemia
SM
Sophia Miliara
Karolinska Institutet
XZ
Xiangfu Zhong
SP
Styliani Papadaki
Science for Life Laboratory
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Key Points
This research explores the potential of ribosome biogenesis as a therapeutic target in acute myeloid leukemia.
Analysis of ribosome biogenesis pathways
Assessment of its impact on cell proliferation in leukemia cells
Exploration of molecular mechanisms involved
Identified key pathways linked to ribosome biogenesis in leukemia cells
Demonstrated altered cell growth related to ribosome function
Highlighted potential targets for new treatments based on these findings
Abstract
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Miliara et al. (Thu,) studied this question.
synapsesocial.com/papers/69be38ca6e48c4981c67965e
https://doi.org/https://doi.org/10.3324/haematol.2025.300149