Tunable Squeeze-Activated GHz Acoustofluidics for Stable Trapping and Separation of Sub 100 nm Nanoparticles

Yiming Liu; Wei Wei; Hang Qi; Shuaihua Zhang; Yongqi Chen; Yaping Wang; Xuexin Duan

doi:10.1039/d6lc00106h

January 1, 2026Lab on a Chip

Tunable Squeeze-Activated GHz Acoustofluidics for Stable Trapping and Separation of Sub 100 nm Nanoparticles

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Key Points

The aim is to achieve stable trapping and separation of sub-100 nm nanoparticles using tunable GHz acoustofluidics.
Developed a GHz acoustofluidic system with tunable parameters
Tested for separation and trapping efficiency of nanoparticles
Evaluated performance stability over time
Achieved stable trapping of sub-100 nm nanoparticles
Enhanced separation efficiency compared to conventional methods
Demonstrated consistent performance under varying conditions

Implication

This research demonstrates improved separation of sub-100 nm nanoparticles, suggesting enhanced efficiency in biological applications.

Abstract

The precise enrichment and size-selective separation of sub-100 nm biological nanoparticles such as exosomes remain challenging due to their small size and heterogeneity. Conventional GHz acoustofluidic systems suffer from unstable...

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69be38ee6e48c4981c679a97 https://doi.org/10.1039/d6lc00106h

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Tunable Squeeze-Activated GHz Acoustofluidics for Stable Trapping and Separation of Sub 100 nm Nanoparticles

Key Points

Implication

Abstract

Discussion

Cite This Study

Tunable Squeeze-Activated GHz Acoustofluidics for Stable Trapping and Separation of Sub 100 nm Nanoparticles

Key Points

Implication

Abstract

Discussion

Cite This Study

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