What question did this study set out to answer?

To provide an open-source software tool designed for accessing Gene Ontology information and calculating significantly enriched functional terms associated with a user-supplied list of genes.

August 5, 2004BioinformaticsOpen Access

GO::TermFinder—open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes

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Authors

EBElizabeth I. BoyleStanford University SWShuai WengNanchang Institute of Technology JGJeremy GollubAlbert Einstein College of Medicine

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Implication

Software analysis presents an open-source tool to identify significantly enriched Gene Ontology terms from gene lists, highlighting automated functional annotation in genomics.

Key Points

To provide an open-source software tool designed for accessing Gene Ontology information and calculating significantly enriched functional terms associated with a user-supplied list of genes.
Developed GO::TermFinder as an open-source package distributed via the Comprehensive Perl Archive Network (CPAN).
Implemented algorithms to parse Gene Ontology annotations and evaluate statistical enrichment of specific biological categories within gene sets.
Released complete source code and accompanying documentation under an open-source license for public access.
Established an automated pipeline enabling researchers to perform statistical overrepresentation analysis on high-throughput genomic data.

Cite This Study

Boyle et al. (2004) studied this question.

synapsesocial.com/papers/69beeee64a5fc2f42eeefc69 https://doi.org/10.1093/bioinformatics/bth456

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Implication

Software analysis presents an open-source tool to identify significantly enriched Gene Ontology terms from gene lists, highlighting automated functional annotation in genomics.

GO::TermFinder—open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes

Discussion

Member takes

Implication

Key Points

Cite This Study

GO::TermFinder—open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes

Discussion

Member takes

Implication

Key Points

Cite This Study

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