Abstract Posterior reversible encephalopathy syndrome (PRES) is an acute clinico-radiological syndrome characterized by neurological and occasional psychiatric symptoms. It frequently develops in the context of cytotoxic medications, hypertension, and preeclampsia/eclampsia with headache, seizures, and altered sensorium as the common presentation. A 30-year-old female, presented on postpartum lower segment cesarean section (post LSCS) 8 th day to the psychiatry outpatient department with acute onset of psychotic symptoms characterized by delusions of persecution and infestation, blurring of vision, headache, and elevated blood pressure with a clear sensorium. Neuroradiological imaging revealed hypodensity and hyperintensities in the parieto-occipital region consistent with the diagnosis of PRES with an electroencephalogram showing epileptiform activity. Conservative management brought about the significant clinical improvement of both her physical and psychological symptoms. It is important to consider organicity as a differential diagnosis in postpartum psychosis. PRES is usually a reversible condition that has a favorable prognosis. Prompt recognition and management enable the prevention of neurological complications and disability, especially in patients with suggestive risk factors.
Mohan et al. (Fri,) studied this question.