Ecological study shows rising thyroid cancer incidence in urban areas versus rural, indicating a need for improved surveillance and prevention strategies.
Key Points
To analyze thyroid cancer incidence rates in China and understand its spatiotemporal distribution.
Analyzed national registry data from the China Cancer Registry (2005-2018)
Employed Joinpoint regression to assess time trends
Used age-period-cohort model for incidence analysis
Applied spatial autocorrelation to evaluate distribution patterns
Age-standardized incidence rate of thyroid cancer was 8.69 per 100,000
Observation of upward trend with an average annual percent change of 10.7%
Higher incidence in urban areas compared to rural
Incidence risk trend varies with age, showing initial increase then decline
Northeastern China displayed high-high clustering patterns