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March 22, 2026Journal of Clinical MedicineOpen Access

Clonal Hematopoiesis in Cardiovascular Risk: Focus on Inflammatory Mechanisms

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Authors

SSSiamala SinnaduraiMHMichael C. HonigbergWMWouter C. Meijers

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Overview

This review demonstrates the role of clonal hematopoiesis in cardiovascular disease, indicating inflammatory mechanisms may contribute to atherosclerosis progression.

Key Points

  • This review summarizes the relationship between clonal hematopoiesis and cardiovascular risk, focusing on inflammation.
  • Review of current literature on clonal hematopoiesis and cardiovascular disease.
  • Analysis of inflammatory mechanisms related to hematopoietic stem cell mutations.
  • Identified roles of DNMT3A mutations in promoting inflammation.
  • Clarified associations between clonal hematopoiesis and atherosclerosis progression.

Cite This Study

Sinnadurai et al. (2026) studied this question.

synapsesocial.com/papers/69bf393dc7b3c90b18b43931https://doi.org/10.3390/jcm15062393
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