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Predictors of Mortality and Clinical Outcomes in Adult Bacterial Meningitis in Northern Vietnam: A Seven-Year Cohort Analysis

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Cohort analysis identifies key mortality predictors in adults with bacterial meningitis, suggesting targeted interventions could improve outcomes.

To identify predictors of mortality and clinical outcomes in adult bacterial meningitis cases in northern Vietnam.
Retrospective-prospective observational cohort study
Included adults diagnosed with bacterial meningitis from 2018 to 2024
Analyzed clinical characteristics, cerebrospinal fluid parameters, and culture results
Used multivariate logistic regression to identify predictors of mortality and unfavourable outcomes
Identified pathogens in 41% of cases, with S. suis as the most common pathogen (26 cases)
Overall mortality rate was 5% and 10% of patients had unfavourable outcomes
Independent predictors include: alcoholism (unfavourable outcome OR 13.8, mortality OR 16.5), focal neurological deficits (unfavourable outcome OR 41.4, mortality OR 12.8), and altered mental status (OR 8.6).

The et al. (2026) studied this question.

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Cohort analysis identifies key mortality predictors in adults with bacterial meningitis, suggesting targeted interventions could improve outcomes.