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March 22, 2026Indian Journal of Critical Care MedicineOpen Access

Clinical Profile and Survival Outcomes of Children with Acute Kidney Injury Requiring Renal Replacement Therapy: A Retrospective Study from a Tertiary Pediatric Intensive Care Unit

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Authors

SSSwarnim SwarnimAGArnab GhoruiSKSneh Kumar

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Overview

This retrospective study evaluates mortality predictors and survival outcomes of pediatric AKI requiring RRT, highlighting clinical implications.

Key Points

  • This study aims to evaluate the causes and outcomes of renal replacement therapy in children with acute kidney injury.
  • Retrospective observational study in a pediatric intensive care unit
  • Included children aged 1 month to 18 years receiving RRT for AKI
  • Data extraction from medical records on demographics, clinical data, and laboratory results
  • Analysis using logistic regression and survival analysis techniques
  • Out of 40 patients, 70% received hemodialysis and 30% peritoneal dialysis
  • Overall in-hospital mortality rate was 27.5%
  • Sepsis was the most common cause of AKI requiring RRT in 39.5% of cases
  • Higher percentage of fluid overload in non-survivors (16.8% vs 8.3%)
  • Increased mortality risk associated with peritoneal dialysis (HR=4.41)

Cite This Study

Swarnim et al. (2026) studied this question.

synapsesocial.com/papers/69bf86ecf665edcd009e902ahttps://doi.org/10.5005/jp-journals-10071-25162
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical profile of pediatric acute renal failure patients requiring renal replacement therapy age less than 15 years: an ambivalent COHORT study2024
  2. 2Renal Replacement Therapy in Pediatric Cardiac Intensive Care: A Retrospective Analysis of Modalities, Outcomes, and Prognostic Factors2025
  3. 3An epidemiological assessment of hemodialysis, continuous kidney replacement therapy, and peritoneal dialysis in pediatric acute kidney injury patients2026
  4. 4Association between renal replacement therapy and in-hospital mortality in patients with severe acute kidney injury: a retrospective cohort study based on MIMIC-IV database2026 · 1 citations
  5. 5Clinical Characteristics and Outcome of Children Requiring First-Time Hemodialysis Over a Year: A Tertiary Center Cohort Study.2024