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March 22, 2026International Journal of Radiation Biology0 citations

Alterations in the testicular lipidome after tumor irradiation and their potential modulation by long-term losartan treatment

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INInês NobreHospitais da Universidade de CoimbraPDPedro DominguesUniversity of AveiroHFHelena Beatriz FerreiraRede de Química e Tecnologia

Key Points

  • This research investigates how radiation affects the lipid makeup of testicular tissue and assesses losartan's role in mitigating these effects.
  • Analysis of lipidomic changes in testicular tissue after tumor irradiation
  • Assessment of morphological data pertaining to testicular function
  • Long-term treatment with losartan to evaluate its protective effects
  • Lipidomic changes correspond with previous findings on testicular morphological changes
  • Losartan appears to help maintain testicular function post-irradiation, minimizing damage from radiation

Abstract

These lipidomic findings support previous morphological data indicating that losartan helps preserve testicular function, minimizing the effects of radiation.

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Cite This Study

Nobre et al. (2026) studied this question.

synapsesocial.com/papers/69bf86ecf665edcd009e9030https://doi.org/10.1080/09553002.2026.2643760
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