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March 19, 2026Revista Española de QuimioterapiaOpen Access

Intravenous non-specific immunoglobulins as adjunctive therapy for invasive Streptococcus pyogenes infection: an eleven-year retrospective study

José María Gutiérrez-Urbón Luis Margusino-Framiñán David Brandariz-Núñez María Sandra Albiñana Pérez Enrique Alemparte-Pardavila Laura Caeiro-Martínez Mónica Mourelo Fariña

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Key Points

This study aims to evaluate the effectiveness of intravenous immunoglobulins (IVIG) as adjunctive therapy for invasive Streptococcus pyogenes infections.
Conducted a retrospective analysis over eleven years
Examined the impact of high-dose IVIG with targeted antibiotics
Assessed patient outcomes related to mortality rates
Mortality rates were similar to or lower than previously reported
Initial disease severity, hepatic dysfunction, and CRRT need increased mortality risk
IVIG showed a favorable safety profile during treatment

Implication

Retrospective study finds intravenous immunoglobulins reduce mortality in invasive infections, indicating efficacy.

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Cite This Study

Gutiérrez-Urbón et al. (2026) studied this question.

synapsesocial.com/papers/69bf86ecf665edcd009e9034 https://doi.org/10.37201/req/125.2026

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