Aims and objectives: This study aims to assess the effectiveness of platelet-rich plasma (PRP) in cesarean wound healing.It enables us to assess how PRP, when given during cesarean wound closure, can improve wound quality and avoid surgical site infection (SSI).Methodology: This was a randomized control trial (RCT) which incorporated 44 women who were divided into two groups after following the inclusion and exclusion criteria.The patients in the case group were administered a subcutaneous injection of autologous PRP during cesarean, which was prepared in our lab.Whereas, the patients in the control group were managed by the existing hospital protocol.The patients were then assessed on day 3, 8/10, and 42 using the redness, edema, ecchymosis, discharge, and approximation (REEDA) scale. Results:The proportion of patients with SSI was significantly lower in the case group (4.55%) compared to the control group (31.82%) with a p-value of 0.046.The mean REEDA on day 8/10 was 1.77 0.61 for the case group, which was significantly lower than the control group (3.27 2.1) with a p-value of 0.009.Similarly, the mean REEDA on day 42 was found to be 0.55 0.51 and 1.41 1.01 for the case and control groups, respectively, the difference of which was statistically significant.There was no statistically significant difference in terms of length of hospital stay.Most of the infections were of a superficial nature.Conclusion: Prophylactic administration of autologous PRP during cesarean wound closure was found to significantly improve wound quality and reduce the development of SSI in the postoperative period.Therefore, our study recommends the use of autologous PRP for a seamless postoperative experience for the patient.
Mitali et al. (Fri,) studied this question.