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Three cases report severe outcomes of acute glomerulonephritis and hemolytic anemia in infants, highlighting critical health risks.
Three cases of acute glomerulonephritis in infancy are reported. The clinical course was dominated by vomiting, diarrhea, convulsions and a marked anemic tendency with hepatosplenomegaly. Anuria developed in two cases. All infants died with signs of heart failure. Both hematologic and pathologic evidence indicated a hemolytic type of anemia. The renal lesions were characterized by cellular proliferation, thickening of the capillary basement membranes and hyaline necrosis of capillary loops and segments of the tufts.
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Jon O. Lamvik (1962) studied this question.
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