Surgical Management of Zollinger‐Ellison Syndrome in Multiple Endocrine Neoplasia Type 1 an AFCE and GTE Cohort Study. (Association Francophone de Chirurgie Endocrinienne and Groupe d'étude des Tumeurs Endocrines)

Key Points

The study aims to investigate surgical management effectiveness for Zollinger‐Ellison Syndrome in Multiple Endocrine Neoplasia Type 1 patients.
Cohort study including patients from AFCE and GTE
Evaluation of surgical outcomes, including lymphadenectomy
Analysis of survival rates and operative mortality for ZES patients
High rate of invaded nodes in lymphadenectomies for MEN1 patients
No operative mortality reported
Decreased survival observed in metastatic patients

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Cohort study reveals surgical benefits for Zollinger‐Ellison Syndrome in MEN1 patients, highlighting lymphadenectomies and gastrinoma outcomes.

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Gaujoux et al. (2026) studied this question.

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