Rare Presentation of Myxoid Pleomorphic Liposarcoma in Cervical Prevertebral Region

Myxoid pleomorphic liposarcoma (MPLS) is a rare subtype of liposarcoma, with the mediastinum being the most common site.Prevalence in the head and neck region is extremely rare.These tumors are very aggressive due to the presence of TP53 mutation and widespread loss of heterozygosity (LOH).These tumors are usually asymptomatic and therefore diagnosed at advanced stages.Surgery followed by adjuvant chemoradiation remains the mainstay of treatment.We report a case of MPLS at a very rare location, the cervical prevertebral region (C4-D3).