Factors Associated with Life-threatening Outcome in Drug Poison Reports in Taiwan Children (1991-2020)

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This research aims to identify factors associated with severe to fatal outcomes in pediatric drug poisoning cases in Taiwan.
Conducted a retrospective analysis using the Taiwan Poison Control Center database from 1991 to 2020.
Examined demographic data, poisoning characteristics, substances involved, and clinical outcomes.
Classified cases into asymptomatic/moderate and severe/fatal categories.
Utilized statistical analyses to identify significant factors linked to severe outcomes.
Only 1.0% of cases were severe to fatal, corresponding to an overall mortality rate of 0.26%.
Severe cases peaked in early childhood (49.7%) and late adolescence (42.3%).
Organophosphates, anticonvulsants, and amphetamines were the most common toxic substances.
Intentional exposures constituted 38.9% of severe cases, with a notable portion being suicide attempts (55.9%).
Prolonged exposure, intentionality, and pesticide use significantly increased the risk of severe outcomes.

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Retrospective analysis explores factors leading to severe outcomes in Taiwanese children, suggesting targeted prevention is vital.

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Tseng et al. (2026) studied this question.

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