Topical treatment with Portulaca oleracea improves wound healing in rats, suggesting potential therapeutic applications.
In a rat model of fecal-contaminated dorsal skin wound infection, topical POL treatment was associated with improved histological outcomes, reduced inflammation, and increased VEGF-related markers. These findings suggest a potential role for POL in promoting infected wound healing, although the VEGF involvement is based on associative expression data and requires further mechanistic validation.
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Fang et al. (2026) studied this question.
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