Monitoring and adjusting antiseizure medications optimizes treatment for women with epilepsy, indicating their fetal safety implications.
Therapeutic drug monitoring is a valuable tool for tailoring antiseizure treatment in women with epilepsy. When monitoring is not feasible, clinicians may need to adjust doses based on seizure severity and the well-documented pharmacokinetic changes of specific medications such as lamotrigine, levetiracetam, oxcarbazepine. The goal is to maintain effective seizure control while minimizing teratogenic risks and ensuring safe fetal development.
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Falcicchio et al. (2026) studied this question.
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