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March 24, 2026European Respiratory Journal

Comparison between patients with idiopathic pulmonary fibrosis and patients with pulmonary involvement of the usual interstitial pneumonia pattern that preceded the onset of rheumatoid arthritis

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Authors

TNTakakiyo NakayaMBMasashi BandoMNMasayuki Nakayama

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Overview

Retrospective study compares prognosis in idiopathic pulmonary fibrosis and RA-UIP patients, indicating better outcomes for RA-UIP.

Key Points

  • This study aims to evaluate clinical differences in prognosis between idiopathic pulmonary fibrosis (IPF) and rheumatoid arthritis-related usual interstitial pneumonia (RA-UIP).
  • Retrospective analysis of 50 patients with UIP diagnosed through video-assisted thoracoscopic surgery or autopsy.
  • Participants were categorized into three groups: RA-UIP, Seropositive, and Seronegative.
  • Survival times of the groups were compared.
  • Median survival time for the RA-UIP group was 107.6 months, significantly longer than Seronegative (26.6 months) and Seropositive (31.2 months) groups.

Cite This Study

Nakaya et al. (2014) studied this question.

synapsesocial.com/papers/69c2296aaeb5a845df0d3dd1https://doi.org/10.1183/13993003/erj.44.suppl_58.p724
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Variable course of disease of rheumatoid arthritis-associated usual interstitial pneumonia compared to other subtypes2016 · 83 citations
  2. 2Rheumatoid arthritis and idiopathic pulmonary fibrosis: a bidirectional Mendelian randomisation study2024 · 29 citations
  3. 3AB0774 ANALYSIS OF A COHORT OF PATIENTS WITH RHEUMATOID ARTHRITIS AND INTERSTITIAL LUNG DISEASE2024
  4. 4B35-51 When the Lungs Speak Up: UIP Pattern ILD Presenting as Primary Symptom of Underlying Untreated Rheumatoid Arthritis2026
  5. 5Radiological diversity in rheumatoid arthritis associated with usual interstitial pneumonia (RA-UIP) and its therapeutic implications: towards a generalizable framework of interstitial lung disease treatment2026