Novel research demonstrates emodin improves rheumatoid arthritis by targeting ferroptosis, suggesting new treatment possibilities.
EMO ameliorates experimental arthritis mainly by suppressing ferroptosis via the GPX4/ACSL4 axis, highlighting ferroptosis as a previously underappreciated therapeutic target in RA and supporting EMO as a potential adjunctive treatment for RA.
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Zhou et al. (2026) studied this question.
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