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A case documents hallucinations in an older adult after lisinopril use, suggesting careful drug evaluation is needed.
Background Lisinopril is generally well tolerated, but rare neuropsychiatric adverse effects have been reported. Case We describe an 89‐year‐old woman who developed vivid nocturnal auditory and visual hallucinations approximately 3 months after starting lisinopril for hypertension. Neurologic examination, imaging, and laboratory evaluation were unremarkable. Hallucinations resolved completely within 2 weeks of drug discontinuation, with no recurrence on follow‐up. Conclusion Older adults may be particularly susceptible to medication‐induced neuropsychiatric effects. Recognition of lisinopril as a reversible cause of hallucinations is essential to avoid misdiagnosis and unnecessary treatment.
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Golder et al. (2026) studied this question.
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