January 1, 1987Journal of Cardiovascular Pharmacology

Lisinopril in Elderly Patients with Hypertension

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Why the study?

Does lisinopril reduce blood pressure in elderly patients with mild to moderate hypertension?

Population

40 elderly patients with mild to moderate systolic/diastolic or isolated systolic hypertension.

Design

Cohort, open-label

Follow-up

12 weeks

Authors

MLM. S. LaherUniversity of the Witwatersrand DND NatinRotunda Hospital SRSatya RaoNew York University

Discussion

Member takes

Implication

Lisinopril-associated BP reduction in elderly mild-moderate hypertension supports consideration; leaves open confirmation in randomized trials.

Structured PICO

Does lisinopril reduce blood pressure in elderly patients with mild to moderate hypertension?

Population

40 elderly patients (aged ≥65 years) with mild to moderate systolic/diastolic or isolated systolic hypertension.

Intervention

Lisinopril oral single daily dose (starting 5-10 mg based on GFR, titrated up to maximum 40 mg daily), with optional addition of thiazide diuretic if uncontrolled, for 12 weeks.

Outcome

Mean sitting blood pressure reduction and safetysurrogate

Lisinopril is an effective and well-tolerated antihypertensive therapy for elderly patients with mild to moderate hypertension.

Cite This Study

Laher et al. (1987) studied this question.

synapsesocial.com/papers/6a72724cfe4101aa97e0da54 https://doi.org/10.1097/00005344-198700003-00017

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Implication

Lisinopril-associated BP reduction in elderly mild-moderate hypertension supports consideration; leaves open confirmation in randomized trials.

Lisinopril in Elderly Patients with Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Lisinopril in Elderly Patients with Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider