Described herein is a chemoselective gem-dihalocyclopropanation of 1,3-enynes by the utilization of Cs₂CO₃ as a base to promote the gem-dihalocarbenes species generation, providing an efficient synthetic approach to various tetrasubstituted cyclopropanes. The present protocol with excellent functional group tolerance, scalability, as well as versatile transformation of the products.
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Liu et al. (2026) studied this question.
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