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Retrospective observational study compares outcomes of oral cephalosporin and penicillin therapies for gram-negative bloodstream infections, suggesting both are effective.
Oral cephalosporins were noninferior to oral penicillins as step-down therapy for Enterobacterales GNBSI. This represents the first comparison of oral beta-lactams for the treatment of GNBSI.
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Volkmar et al. (2026) studied this question.
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