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March 25, 2026INROADS- An International Journal of Jaipur National University

Triple Biomarkers in the Early Diagnosis of Acute Kidney Injury: a Comprehensive Review

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Authors

MVM. VijayasimhaTCTejulal Prasad ChaurasiaMAMonica Acharya

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Overview

This review examines biomarkers for early AKI detection, suggesting improvements in diagnosis and patient outcomes.

Key Points

  • To evaluate emerging biomarkers for the early detection of acute kidney injury and their clinical implications.
  • Comprehensive review of current literature on AKI biomarkers.
  • Analysis of sensitivity and specificity of Cystatin C, NGAL, and KIM-1.
  • Discussion of integration of biomarkers into clinical workflows.
  • Cystatin C shows reliability as an alternative to creatinine for diagnosing AKI.
  • NGAL has high sensitivity for detecting early kidney injury.
  • KIM-1 indicates injury severity and prognosis after kidney damage.

Cite This Study

Vijayasimha et al. (2025) studied this question.

synapsesocial.com/papers/69c37bb3b34aaaeb1a67e57bhttps://doi.org/10.5958/2277-4912.2025.00001.8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Kidney Injury and Early Diagnostic Biomarkers: A Narrative Literature Review.2026 · 1 citations
  2. 2Emerging Biomarkers in Kidney Function Assessment: From Conventional Tests to Precision Diagnostics2026
  3. 3Novel Biomarkers for Kidney Disease: New Frontiers in Early Diagnosis and Monitoring2024 · 2 citations
  4. 4Novel biomarkers for acute kidney injury in high-risk pediatric populations: a systematic review2026
  5. 5Novel molecular biomarkers in kidney diseases: bridging the gap between early detection and clinical implementation2025 · 3 citations