What question did this study set out to answer?

This review aims to summarize the evidence linking human milk oligosaccharides to infant neurodevelopment and cognitive outcomes.

Human Milk Oligosaccharides (HMOs) in Infant Neurodevelopment: Evidence Linking Gut–brain Signaling to Cognitive Outcomes

View Full Paper

Ask AI

Bookmark

Authors

Narrative review shows HMOs link gut-brain signaling to improved cognitive outcomes in infants, suggesting dietary importance.

This review aims to summarize the evidence linking human milk oligosaccharides to infant neurodevelopment and cognitive outcomes.
Conducted structured searches on PubMed, Scopus, and Web of Science for literature from 2000 to 2025.
Included observational cohort studies, mechanistic research, and preclinical models.
Examined various neurodevelopmental outcomes such as cognitive function and language skills.
Exposure to specific HMOs, especially fucosylated and sialylated types, is associated with improved cognitive performance.
Infants with higher HMO levels show better language development and behavioral regulation.
Biological mechanisms include the promotion of beneficial gut microbiota and immune regulation.

Haque et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark