Enantioselective cascade reactions construct high-selectivity chiral scaffolds, indicating potential in anti-tumour applications.
An enantioselective Michael/O-alkylation cascade between hydroxyquinolines and chloronitroalkenes was developed, constructing chiral dihydrofuroquinoline scaffolds in high enantioselectivity under mild conditions. The direct modification of hydroxylcamptothecin and the discovery of anti-tumour...
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Wang et al. (2026) studied this question.
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