What question did this study set out to answer?

This study aims to assess the antimicrobial and antibiofilm activities of Butea monosperma flower extract against selected bacteria.

Antimicrobial Activity of Butea monosperma Lam. Flower Extract against Gram-positive and Gram-negative Bacteria

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Evaluates the antimicrobial effects of Butea monosperma flower extract against bacteria, suggesting potential new treatments.

This study aims to assess the antimicrobial and antibiofilm activities of Butea monosperma flower extract against selected bacteria.
Tested ethanolic extract of Butea monosperma against Gram-positive and Gram-negative bacteria
Measured antimicrobial activity using minimum inhibitory concentration (MIC) assays
Assessed biofilm inhibition at varying concentrations
Evaluated postantibiotic effects (PAE) and synergy with cefalexin
Conducted network pharmacology analysis to identify molecular targets and pathways
BMFE exhibited consistent antibacterial activity with a MIC of 2 mg/mL against all strains
Significant biofilm reduction observed in a concentration-dependent manner
Measurable PAE of approximately 2 hours at 4× MIC
Synergistic effect with cefalexin against S. epidermidis (FICI of 0.1875)
Network pharmacology indicated involvement of fatty acid biosynthesis and protein degradation

Khan et al. (2026) studied this question.

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