What question did this study set out to answer?

To evaluate the effects of glutamine and partially hydrolyzed guar gum on intestinal adaptation in a low-birth-weight infant with a high-output stoma.

March 25, 2026JPGN ReportsOpen Access

Glutamine and partially hydrolyzed guar gum promote intestinal adaptation and modulate small intestinal microbiota in high‐output stoma: A case report

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Authors

YKYunosuke KawaguchiChiba University KTKeita TeruiJichi Medical University ATAyako TakenouchiChiba University

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Implication

Case report finds improved weight gain and microbiota shifts after glutamine and PHGG in infants.

Key Points

To evaluate the effects of glutamine and partially hydrolyzed guar gum on intestinal adaptation in a low-birth-weight infant with a high-output stoma.
Administered glutamine and partially hydrolyzed guar gum supplementation.
Monitored stoma output, feeding tolerance, and weight gain.
Conducted histological analysis of intestinal tissue.
Performed microbiota analysis to assess microbial composition.
Reduced stoma output and improved feeding tolerance noted.
Increased weight gain observed in the infant.
Histological analysis revealed villous elongation.
Microbiota analysis showed a shift from Proteobacteria dominance to increased Firmicutes and Actinobacteria.

Cite This Study

Kawaguchi et al. (2026) studied this question.

synapsesocial.com/papers/69c37bf3b34aaaeb1a67ec9d https://doi.org/10.1002/jpr3.70169

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Glutamine and partially hydrolyzed guar gum promote intestinal adaptation and modulate small intestinal microbiota in high‐output stoma: A case report

Discussion

Member takes

Implication

Key Points

Cite This Study

Glutamine and partially hydrolyzed guar gum promote intestinal adaptation and modulate small intestinal microbiota in high‐output stoma: A case report

Discussion

Member takes

Implication

Key Points

Cite This Study

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