Ru-Au Nanocluster-Functionalized Carbon Fiber Microelectrode Enables Ultrasensitive Multiplexed Monitoring of Acetaminophen and Its Genotoxic Interplay with DNA

Tao Fang; Min Shi; Uchkun Ishimov; Ruiting Tian; Jun Li; Han Cheng; Awais Ihsan; Xue Huang

doi:10.1039/d6ay00071a

January 1, 2026Analytical Methods

Ru-Au Nanocluster-Functionalized Carbon Fiber Microelectrode Enables Ultrasensitive Multiplexed Monitoring of Acetaminophen and Its Genotoxic Interplay with DNA

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Key Points

The aim is to create a sensitive sensor for detecting acetaminophen and examining its effects on DNA.
Developed electrochemical sensor using ruthenium-gold nanoclusters on carbon fiber microelectrodes.
Conducted tests to measure the sensitivity and selectivity of the sensor for acetaminophen.
Investigated the interaction between acetaminophen and DNA through electrochemical analysis.
Achieved ultrasensitive detection of acetaminophen at low concentrations.
Demonstrated potential genotoxicity effects of acetaminophen on DNA interactions.
Sensor showed improved selectivity compared to traditional methods.

Implication

Demonstrates a novel sensor detects acetaminophen, indicating its genotoxic effects on DNA.

Abstract

This study presents the development of a highly sensitive and selective electrochemical sensor based on ruthenium-gold nanocluster-functionalized carbon fiber microelectrodes (AuNPs/RuNPs/CFME) for the ultrasensitive detection of acetaminophen (ACOP) and its...

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Cite This Study

Fang et al. (2026) studied this question.

synapsesocial.com/papers/69c37bf3b34aaaeb1a67ed0a https://doi.org/10.1039/d6ay00071a

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Ru-Au Nanocluster-Functionalized Carbon Fiber Microelectrode Enables Ultrasensitive Multiplexed Monitoring of Acetaminophen and Its Genotoxic Interplay with DNA

Key Points

Implication

Abstract

Discussion

Cite This Study

Ru-Au Nanocluster-Functionalized Carbon Fiber Microelectrode Enables Ultrasensitive Multiplexed Monitoring of Acetaminophen and Its Genotoxic Interplay with DNA

Key Points

Implication

Abstract

Discussion

Cite This Study

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