Ru-Au Nanocluster-Functionalized Carbon Fiber Microelectrode Enables Ultrasensitive Multiplexed Monitoring of Acetaminophen and Its Genotoxic Interplay with DNA

Key Points

• The aim is to create a sensitive sensor for detecting acetaminophen and examining its effects on DNA.
• Developed electrochemical sensor using ruthenium-gold nanoclusters on carbon fiber microelectrodes.
• Conducted tests to measure the sensitivity and selectivity of the sensor for acetaminophen.
• Investigated the interaction between acetaminophen and DNA through electrochemical analysis.
• Achieved ultrasensitive detection of acetaminophen at low concentrations.
• Demonstrated potential genotoxicity effects of acetaminophen on DNA interactions.
• Sensor showed improved selectivity compared to traditional methods.