In vivo circumferential strain in the adult aorta is heterogeneous but follows consistent patterns, which is important for future clinical interpretation and computational modeling of aortic kinematics.
Aortic strain heterogeneity challenges uniform kinematic assumptions; extends patient-specific normalization for modeling but leaves clinical adoption open pending validation.
Regional in vivo circumferential strain in the adult aorta is unique to each axial location and heterogeneous around its circumference, but can be grouped into consistent patterns defined by basic patient-specific metrics following normalization. The heterogeneous strain distributions unique to each group may be due to local peri-aortic constraints (particularly at the aorto-vertebral interface), heterogeneous material properties, and/or heterogeneous flow patterns. These results must be carefully considered in future studies seeking to clinically interpret or computationally model patient-specific aortic kinematics.
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Wilson et al. (2019) studied this question.
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