Why the study?
Does 3D regional strain analysis using 3T MRI tagging improve diagnostic accuracy in delineating dysfunctional and nonviable myocardium compared to 1D or 2D strain in a porcine myocardial infarction model?
Does 3D regional strain analysis using 3T MRI tagging improve diagnostic accuracy in delineating dysfunctional and nonviable myocardium compared to 1D or 2D strain in a porcine myocardial infarction model?
3D regional strain analysis using 3T MRI tagging provides superior diagnostic accuracy over 1D or 2D methods for identifying infarcted and adjacent dysfunctional myocardium in a preclinical model.
Supports 3D strain for infarct delineation in porcine models; leaves open clinical translation and human validation.
Cumulative 3D strain information accurately identifies infarcts and their neighboring regions from healthy myocardium. The 3D interrogation of myocardial contractility provides incremental diagnostic accuracy in delineating the dysfunctional and nonviable myocardium in comparison with 1D or 2D quantification of strain. The infarct neighboring regions are the major beneficiaries of the 3D assessment of regional strain.
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Soleimanifard et al. (2012) studied this question.
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