Female sex, non-white race, and higher comorbidity burden are associated with an increased risk of in-hospital major adverse events following left atrial appendage closure.
In this large cohort of LAAC patients, the majority of them had significant comorbidity burden. In-hospital MAE occurred in 4.6% and female patients, non-whites and those with higher burden of comorbidities were at higher risk of in-hospital MAE after LAAC.
Sanjoy et al. (2020) studied this question.
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