What question did this study set out to answer?

To characterize the fine morphological structure of diverse synapses across different regions of the central nervous system.

July 25, 1956The Journal of Cell BiologyOpen Access

Synapses in the Central Nervous System

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To characterize the fine morphological structure of diverse synapses across different regions of the central nervous system.
Ultrastructural examination of synapses within the medulla, cerebellar cortex, and cerebral cortex of rats using electron microscopy.
Synapses demonstrate closely apposed presynaptic and postsynaptic membranes separated by a cleft approximately 200 Å wide with localized membrane thickenings, lacking protoplasmic continuity.
Presynaptic axon terminals consistently contain collections of mitochondria alongside dense clusters of small vesicles measuring 200 to 650 Å in diameter.

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Implication

Microscopic examination reveals conserved synaptic clefts, membrane densities, and vesicle clusters in rat brain regions, suggesting structural units for neurohumoral transmission.

Cite This Study

Sanford L. Palay (1956) studied this question.

synapsesocial.com/papers/69c477a9bfa6f53a8d08677b https://doi.org/10.1083/jcb.2.4.193

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Implication

Microscopic examination reveals conserved synaptic clefts, membrane densities, and vesicle clusters in rat brain regions, suggesting structural units for neurohumoral transmission.

Synapses in the Central Nervous System

Key Points

Discussion

Implication

Cite This Study

Synapses in the Central Nervous System

Key Points

Discussion

Implication

Cite This Study

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