DNA Nanostructures Ions act as key regulators of DNA nanostructures. In their Review (10.1002/sstr.202500786), Sergiy Perepelytsya, Aatto Laaksonen, Francesca Mocci, and co-workers highlight how diverse ion–DNA interactions govern DNA condensation, stability, and nanoscale organization. These mechanisms underpin technologies including DNAzymes, DNA batteries, metallized DNA nanowires, nanopore sensing platforms, and programmable DNA nanostructures, demonstrating how ionic environments guide the design of functional nanoscale systems.
Perepelytsya et al. (Sun,) studied this question.